SCHEMBL1397144

SCHEMBL1397144

CC(C(=O)C(C)(C)C)C(=O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MAPT P10636 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19056892 0.84 TP53 (0.40) TP53ALDH1A1TSHRHSP90AA1MAPT
SCHEMBL2467543 0.84 TP53 (0.40) TP53ALDH1A1TSHRHSP90AA1MAPT
SCHEMBL8459222 0.84
SCHEMBL4799228 0.82
SCHEMBL2355707 0.82 TP53 (0.38) TP53ALDH1A1TSHRHSP90AA1MAPT
SCHEMBL2355710 0.82 TP53 (0.38) TP53ALDH1A1TSHRHSP90AA1MAPT
SCHEMBL8462935 0.82
SCHEMBL30394140 0.82 TP53 (0.38) TP53ALDH1A1TSHRHSP90AA1MAPT
SCHEMBL9127789 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL25199700 0.80 CA1 (0.33) CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2288640-B1 WATER SOLUBLE AMINE AND ITS APPLICATION SIKA TECH AG (CH) 2018-09-19 EP claimed
US-8912294-B2 Polyamine having a reduced blushing effect, and use thereof as a curing agent for epoxy resins SIKA TECHNOLOGY AG (CH) 2014-12-16 US claimed
EP-2288639-B1 POLYAMINE WITH REDUCED BLUSHING AND ITS APPLICATION AS HARDENER FOR EPOXY RESIN SIKA TECHNOLOGY AG (CH) 2014-02-19 EP claimed
US-8524807-B2 Water soluble amine and uses thereof SIKA TECHNOLOGY AG (CH) 2013-09-03 US claimed
US-20110166259-A1 WATER SOLUBLE AMINE AND USES THEREOF SIKA TECHNOLOGY AG (CH) 2011-07-07 US claimed
US-20110082248-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2011-04-07 US claimed
EP-2288640-A1 WATER-SOLUBLE AMINE AND USES THEREOF Sika Technology AG (CH) 2011-03-02 EP claimed
EP-2288639-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS Sika Technology AG (CH) 2011-03-02 EP claimed
WO-2009150219-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2009-12-17 WO claimed
WO-2009150212-A1 WATER-SOLUBLE AMINE AND USES THEREOF SIKA TECHNOLOGY AG (CH) 2009-12-17 WO claimed
EP-2133381-A1 Water soluble amine and its application Sika Technology AG (CH) 2009-12-16 EP claimed
EP-2133378-A1 Polyamine with reduced blushing and its application as hardener for epoxy resin Sika Technology AG (CH) 2009-12-16 EP claimed
CN-1138743-C 1, 3-diketone compound ض� 2004-02-18 CN claimed
CN-1054139-C Catalyst component for the polymerization of olefins and catalyst obtained MONTELL NORTH AMERICAN INC (US) 2000-07-05 CN claimed
CN-1257061-A 1, 3-diketone compound MONTELL NORTH AMERICAN INC (US) 2000-06-21 CN claimed
EP-0646605-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1999-06-02 EP claimed
US-5468704-A Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity MONTELL NORTH AMERICA INC. (US) 1995-11-21 US claimed
CN-1105671-A Components and catalysts for olefin polymerization HIMONT INC (US) 1995-07-26 CN claimed
EP-0646605-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1995-04-05 EP claimed
US-5379718-A Vapor deposition, decomposition of titanium alkoxide or diketone compound, semiconductor wiring SHARP KABUSHIKI KAISHA (JP) 1995-01-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110082248-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS SRM, PRMT1, PBRM1 CA1 3146/4885L3MBTL1 2415/4885TP53 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.