Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7488066 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL7495249 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7484657 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7487574 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7488464 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399198 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL8458587 | 0.81 | SLC1A3 (0.47) | ITGB3ITGA2BCA12CA9 | |
| SCHEMBL7398725 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399762 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7494945 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929120-A | Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5741796-A | Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0760658-A4 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0760658-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO. INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032710-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1995-12-07 | — | — | WO | disclosed |