Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398124 | 0.92 | POLB (0.45) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7398408 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7488066 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL8454597 | 0.84 | ITGB3 (0.44) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7494945 | 0.84 | ITGB3 (0.44) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7402176 | 0.84 | USP2 (0.44) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7402092 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BMMP2ALDH1A1PKM | |
| SCHEMBL7402108 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BKAT6AALDH1A1PKM | |
| SCHEMBL7398725 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1KDM4E | |
| SCHEMBL8801722 | 0.81 | MMP1 (0.44) | ITGB3ITGA2BMMP2KAT6AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929120-A | Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5741796-A | Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1998-04-21 | — | — | US | disclosed |