SCHEMBL8459494

SCHEMBL8459494

COCC(O)CNC(C)(CO)CO

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165425 0.83 CYP2D6 (0.32)
SCHEMBL8962578 0.81 CYP2D6 (0.53)
SCHEMBL14660965 0.81 CASR (0.48)
SCHEMBL11379702 0.78 MAPT (0.42) MAPT
SCHEMBL22000853 0.77 CASR (0.41) MAPT
SCHEMBL11596086 0.77 USP2 (0.58) MAPT
SCHEMBL5530973 0.77 USP2 (0.58) MAPT
SCHEMBL7857829 0.73 LMNA (0.30)
SCHEMBL11702665 0.72 TDP1 (0.36)
SCHEMBL15422990 0.71 USP2 (0.55) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed