SCHEMBL165425

SCHEMBL165425

CC(CO)(CO)NCC(O)CNC(C)(CO)CO

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7857829 0.84 LMNA (0.30)
SCHEMBL8459494 0.83 MAPT (0.41)
SCHEMBL11702665 0.82 TDP1 (0.36)
SCHEMBL14660965 0.80 CASR (0.48)
SCHEMBL114996 0.79 PKM (0.43)
SCHEMBL12228335 0.77 KDM4E (0.30)
SCHEMBL11672858 0.75 KDM4E (0.54)
SCHEMBL7063746 0.75 CYP2D6 (0.48) CYP2D6
SCHEMBL4147093 0.73 ALDH1A1 (0.35)
SCHEMBL11129270 0.72 CYP2D6 (0.34) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8790456-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies ANGUS CHEMICAL COMPANY 2014-07-29 US claimed
US-20140187820-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US claimed
US-20140187678-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US claimed
EP-2424833-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES Dow Global Technologies LLC (US) 2012-03-07 EP claimed
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ADVANCION CORPORATION 2012-02-09 US claimed
WO-2010126962-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-04 WO claimed
EP-2424833-B1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES ANGUS CHEMICAL (US) 2015-07-29 EP disclosed
US-8877979-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-04 US disclosed
US-8790456-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies ANGUS CHEMICAL COMPANY 2014-07-29 US disclosed
US-20140187820-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US disclosed
US-20140187678-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US disclosed
US-8702859-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-22 US disclosed
US-20120245306-A1 ADDUCTS BASED ON DIVINYLARENE OXIDES BLUE CUBE IP LLC 2012-09-27 US disclosed
US-20120245306-A1 ADDUCTS BASED ON DIVINYLARENE OXIDES BLUE CUBE IP LLC 2012-09-27 US disclosed
EP-2424833-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES Dow Global Technologies LLC (US) 2012-03-07 EP disclosed
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ADVANCION CORPORATION 2012-02-09 US disclosed
WO-2011068858-A1 ADDUCTS BASED ON DIVINYLARENE OXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2011-06-09 WO disclosed
WO-2010126962-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES AOC1, DAO, DDO CYP2D6 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.