Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068179 | 0.82 | SLC6A2 (0.38) | HRH3SLC6A2HTR1AADRA2AADRB3 | |
| SCHEMBL24873325 | 0.81 | KDM4C (0.46) | HTR1AOPRK1OPRM1OPRL1KDM4C | |
| SCHEMBL15731953 | 0.79 | OPRM1 (0.35) | HRH3SLC6A2HTR1AADRA2AADRB3 | |
| SCHEMBL18407453 | 0.74 | NOTUM (0.53) | HTR1AOPRK1DRD2 | |
| SCHEMBL709502 | 0.70 | EEF2K (0.41) | SLC6A2ADRA1ASLC6A3OPRM1SLC6A4 | |
| SCHEMBL8244093 | 0.69 | CCKBR (0.44) | HRH3SLC6A2HTR1AADRA2AADRB3 | |
| SCHEMBL13068132 | 0.69 | PRKACA (0.33) | HRH3SLC6A2HTR1AADRA2AADRA1A | |
| SCHEMBL15818537 | 0.69 | KDM4C (0.45) | HTR2CMEN1USP2GAAKMT2A | |
| SCHEMBL20244050 | 0.68 | OPRM1 (0.38) | OPRK1OPRM1OPRL1MEN1GAA | |
| SCHEMBL18373678 | 0.68 | SLC6A2 (0.38) | HRH3SLC6A2HTR1AADRA2AADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918774-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997049709-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-31 | — | — | WO | disclosed |