Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871004 | 0.86 | KDM4E (0.60) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL27532290 | 0.81 | HTR2A (0.68) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL4558490 | 0.79 | HTT (0.55) | ADRA1AADRA1BDRD4HTR2ACCR5 | |
| SCHEMBL24726680 | 0.79 | OPRD1 (0.76) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL3094944 | 0.78 | OPRM1 (0.68) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL17275267 | 0.78 | HTT (0.54) | CCR5MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL1519356 | 0.78 | HTR2A (0.75) | OPRM1SIGMAR1HTR2A | |
| SCHEMBL27300983 | 0.78 | HTR2A (0.75) | OPRM1SLC6A3KCNH2SIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL31093248 | 0.78 | OPRD1 (0.74) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL3087687 | 0.78 | ACHE (0.60) | OPRM1OPRD1OPRK1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043323-A1 | COMPOUNDS AND METHODS FOR CHEMOSENSITIZING MULTIDRUG RESISTANT CELLS | FOX CHASE CANCER CENTER (US) | 1999-09-02 | — | — | WO | disclosed |