Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 4/20 | 0.60 |
| ▸ | GNG2 | P59768 | 1/20 | 0.53 |
| ▸ | GNB1 | P62873 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300312 | 0.84 | GNG2 (0.74) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL29756254 | 0.84 | GNG2 (0.74) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL8459003 | 0.77 | GNG2 (0.47) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL31001054 | 0.77 | GNG2 (0.50) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL8458720 | 0.76 | FTO (0.66) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL8417826 | 0.76 | FTO (0.73) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL7970168 | 0.75 | FTO (0.60) | FTOGNG2GNB1MEN1KMT2A | |
| SCHEMBL220211 | 0.75 | FTO (1.00) | FTOMEN1KMT2AMAPTLMNA | |
| SCHEMBL29413057 | 0.75 | FTO (1.00) | FTOMEN1KMT2AMAPTLMNA | |
| SCHEMBL17201722 | 0.74 | GNG2 (0.76) | FTOGNG2GNB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922612-A | INDEPENDENT, REVERSIBLE FLUORESCENCE SPECTROMETRY OF SAMPLE USING TWO OPTICAL SENSORS COMPOSED OF A CARRIER EACH COATED WITH DIFFERENT WATER INSOLUBLE BUT HYDROPHILIC ADDITION POLYMER LOADED WITH THE SAME FLUORESCENT DYE | NOVARTIS CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0758451-B1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | NOVARTIS AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| EP-0881241-A2 | Copolymers and dyes for optical pH sensors | Novartis AG (CH) | 1998-12-02 | — | — | EP | disclosed |
| EP-0758451-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030148-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |