SCHEMBL8417826

SCHEMBL8417826

Cc1c(O)ccc2c1Oc1cc(O)ccc1C21OC(=O)c2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.73
MAPT P10636 6/20 0.73
MEN1 O00255 5/20 0.73
KMT2A Q03164 5/20 0.73
TDP1 Q9NUW8 4/20 0.73
HTT P42858 2/20 0.73
CYP2C19 P33261 2/20 0.73
RECQL P46063 2/20 0.73
BLM P54132 2/20 0.73
PRMT1 Q99873 2/20 0.73
ACE2 Q9BYF1 2/20 0.73
HPGD P15428 1/20 0.73
SMAD3 P84022 1/20 0.73
LMNA P02545 5/20 0.62
POLB P06746 2/20 0.62
GPR55 Q9Y2T6 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
ALOX12 P18054 1/20 0.62
GNG2 P59768 1/20 0.58
GNB1 P62873 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4487538 0.91 FTO (0.67) FTOMAPTMEN1KMT2ATDP1
SCHEMBL31326016 0.88 FTO (0.76) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29756254 0.88 GNG2 (0.74) FTOMAPTMEN1KMT2ATDP1
SCHEMBL2300312 0.88 GNG2 (0.74) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5066567 0.87 FTO (0.74) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5775292 0.86 FTO (0.70) FTOMAPTMEN1KMT2ATDP1
SCHEMBL8607854 0.86 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5359408 0.86 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL3652107 0.86 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL20907331 0.86 FTO (0.73) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120045851-A1 LABELS, THEIR PRODUCTION PROCESS AND THEIR USES LABORATOIRES SYNTH-INNOVE (FR) 2012-02-23 US disclosed
US-8034626-B2 Labels, their production process and their uses LABORATOIRES SYNTH-INNOVE (FR) 2011-10-11 US disclosed
US-20080318336-A1 Labels, Their Production Process And Their Uses LABORATOIRES SYNTH-INNOVE (FR) 2008-12-25 US disclosed
US-5986094-A XANTHENE DYES AND PHTHALEIN DYES FOR FLUORESCEENT DYES ROCHE DIAGNOSTICS CORPORATION (US) 1999-11-16 US disclosed
US-5986094-A XANTHENE DYES AND PHTHALEIN DYES FOR FLUORESCEENT DYES ROCHE DIAGNOSTICS CORPORATION (US) 1999-11-16 US disclosed
US-5776720-A COMPOUND OR SALT FOR ASSAYING ACTIVITY OF AN ENZYME INSIDE A METABOLICALLY ACTIVE WHOLE CELL COULTER CORPORATION (US) 1998-07-07 US disclosed
EP-0832279-A1 AN ASSAY REAGENT AND A METHOD OF MAKING AND USING THE ASSAY REAGENT Coulter International Corp. (US) 1998-04-01 EP disclosed
WO-1996036729-A1 AN ASSAY REAGENT AND A METHOD OF MAKING AND USING THE ASSAY REAGENT COULTER INTERNATIONAL CORP. (US) 1996-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045851-A1 LABELS, THEIR PRODUCTION PROCESS AND THEIR USES HLCS, PFAS, CYBA FTO 191/4885MAPT 1415/4885MEN1 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.