Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL36962 | 0.96 | TSHR (0.61) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Tetramethylammonium Ion SCHEMBL3909246 | 0.92 | TSHR (0.57) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Tetramethylammonium Ion SCHEMBL28051064 | 0.92 | TSHR (0.57) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Tetramethylammonium Ion SCHEMBL15348713 | 0.89 | MEN1 (0.53) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Tetramethylammonium Ion SCHEMBL28468866 | 0.86 | TSHR (0.50) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL11797353 | 0.81 | TSHR (0.53) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL155382 | 0.79 | — | — | |
| Tetramethylammonium Ion SCHEMBL36961 | 0.79 | CHRNB2 (0.40) | TSHRMEN1ALDH1A1KMT2ABBOX1 | |
| Tetramethylammonium Ion SCHEMBL2910816 | 0.79 | CA5A (0.60) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL7140465 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863838-A | Method for chemically-mechanically polishing a metal layer | MOTOROLA, INC. (US) | 1999-01-26 | — | — | US | disclosed |