Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594962 | 0.96 | ALDH1A1 (0.48) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL11669339 | 0.96 | ALDH1A1 (0.48) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL7632484 | 0.88 | ALDH1A1 (0.52) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL28172405 | 0.86 | LMNA (0.50) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10337633 | 0.84 | FFAR4 (0.46) | LMNAFFAR4FFAR1 | |
| SCHEMBL10539376 | 0.83 | FFAR1 (0.41) | LMNATDP1CYP3A4ATMFFAR4 | |
| SCHEMBL4652968 | 0.82 | CA2 (0.55) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL4655227 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10583722 | 0.79 | CA2 (0.42) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10406984 | 0.79 | ALDH1A1 (0.50) | LMNAALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944661-A1 | INNER PARTING AGENTS FOR PRODUCING SELF-PARTING MOULDINGS MADE OF POLYISOCYANATE POLYADDITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025985-A1 | INNER PARTING AGENTS FOR PRODUCING SELF-PARTING MOULDINGS MADE OF POLYISOCYANATE POLYADDITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |