Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463164 | 0.82 | GRIN2D (0.42) | MPLGPR35DHODHPOLBAKR1C3 | |
| SCHEMBL8462693 | 0.78 | MPL (0.38) | MPLGPR35ASPHEPRS1CES2 | |
| SCHEMBL8464099 | 0.74 | ASPH (0.46) | ASPHCES2NOTUMAKR1C3AKR1C2 | |
| SCHEMBL8461015 | 0.74 | GPR35 (0.37) | GPR35CES2POLBAKR1C2GRIN2D | |
| SCHEMBL8464883 | 0.71 | KDM4E (0.49) | GPR35DHODHPOLBGRIN2DGRIN2A | |
| SCHEMBL8459474 | 0.71 | GRIN2D (0.45) | GPR35POLBNOTUMGRIN2DGRIN2A | |
| SCHEMBL8462722 | 0.69 | GRIN2D (0.68) | GPR35POLBGRIN2DGRIN2AGRIN2B | |
| SCHEMBL4647359 | 0.68 | ALDH1A1 (0.43) | ASPHCES2NOTUMKDM4EALDH1A1 | |
| SCHEMBL8463690 | 0.68 | GRIN2D (0.45) | GPR35POLBNOTUMGRIN2DGRIN2A | |
| SCHEMBL8462125 | 0.68 | GRIN2D (0.45) | GPR35POLBGRIN2DGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |