Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464700 | 0.76 | TSHR (0.49) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8464782 | 0.73 | HSD17B10 (0.38) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8461798 | 0.73 | HSD17B10 (0.38) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8464814 | 0.73 | KDM4E (0.41) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL5664709 | 0.73 | ALDH1A1 (0.70) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6916678 | 0.71 | ALDH1A1 (0.68) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6915788 | 0.71 | ALDH1A1 (0.68) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6916682 | 0.71 | ALDH1A1 (0.68) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6916880 | 0.71 | ALDH1A1 (0.68) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6913595 | 0.71 | ALDH1A1 (0.68) | TSHRALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |