Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902117 | 0.90 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL10608002 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL1253678 | 0.83 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL141271 | 0.83 | TSHR (0.44) | TSHRALDH1A1THRBHPGDATM | |
| SCHEMBL11740485 | 0.81 | TSHR (0.42) | TSHRALDH1A1THRBHPGD | |
| SCHEMBL9309592 | 0.78 | TSHR (0.46) | TSHRALDH1A1THRBHPGDLMNA | |
| SCHEMBL3903524 | 0.78 | TSHR (0.50) | TSHRALDH1A1THRBLMNA | |
| SCHEMBL10605213 | 0.78 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL8458243 | 0.77 | TSHR (0.51) | TSHRALDH1A1THRBHPGDLMNA | |
| SCHEMBL1133079 | 0.76 | TSHR (0.41) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604677-B1 | Method of making coated shaped articles | MITSUBISHI RAYON CO (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5470616-A | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0604677-A1 | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-4133938-A | ACRYLOYLOXYALKYLALKOXYSILANE-ACRYLATE REACTION PRODUCT, MASONRY | SWS SILICONES CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4029842-A | POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-06-14 | — | — | US | disclosed |