Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460675 | 0.90 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL1253678 | 0.86 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL193617 | 0.81 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL11740826 | 0.80 | TSHR (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL16115100 | 0.78 | THRB (0.37) | TSHRTHRB | |
| SCHEMBL16537597 | 0.77 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL11585005 | 0.77 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL8461587 | 0.76 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL193159 | 0.76 | ALDH1A1 (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL28515062 | 0.74 | TSHR (0.36) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7510775-B2 | Composition based on isotactic polypropylene obtained by metallocene catalysis and on grafted isotactic polypropylene obtained by ziegler-natta catalysis | ARKEMA FRANCE (FR) | 2009-03-31 | — | — | US | disclosed |
| US-7459214-B2 | Binder and a packaging laminate comprising the binder | TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) | 2008-12-02 | — | — | US | disclosed |
| EP-1283227-B1 | Graft polymer from Isotactic polypropylene obtained with a metallocene catalyst | ARKEMA FRANCE (FR) | 2007-01-31 | — | — | EP | disclosed |
| US-7067196-B2 | Grafted syndiotactic polypropylene and coextruding binders based on syndiotactic polypropylene | ARKEMA (FR) | 2006-06-27 | — | — | US | disclosed |
| US-20060134355-A1 | Binder and a packaging laminate comprising the binder | TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) | 2006-06-22 | — | — | US | disclosed |
| EP-1599558-B1 | A BINDER AND A PACKAGING LAMINATE COMPRISING THE BINDER | TETRA LAVAL HOLDINGS & FINANCE (CH) | 2006-06-14 | — | — | EP | disclosed |
| EP-1609593-A2 | Packaging material including a silica layer and a polyolefin layer | Arkema (FR) | 2005-12-28 | — | — | EP | disclosed |
| EP-1599558-A1 | A BINDER AND A PACKAGING LAMINATE COMPRISING THE BINDER | TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) | 2005-11-30 | — | — | EP | disclosed |
| CN-1219816-C | Isotactic polypropylene and composition with graft isotactic polypropylene as main ingredient | ATOFINAS S A (FR) | 2005-09-21 | — | — | CN | disclosed |
| US-20050192406-A1 | Composition based on isotactic polypropylene obtained by metallocene catalysis and on grafted isotactic polypropylene obtained by ziegler-natta catalysis | ATOFINA S.A. | 2005-09-01 | — | — | US | disclosed |
| EP-0604677-B1 | Method of making coated shaped articles | MITSUBISHI RAYON CO (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5731092-A | POLYOLEFIN BINDER GRAFTED WITH UNSATURATED ALKOXYSILANE OR EPOXIDE; BONDING STRENGTH | ELF ATOCHEM S.A. (FR) | 1998-03-24 | — | — | US | disclosed |
| CN-1130367-A | Packaging material including silica layer and polyolefin layer | ATOCHEM ELF SA (FR) | 1996-09-04 | — | — | CN | disclosed |
| EP-0716631-A1 | PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER | ELF ATOCHEM S.A. (FR) | 1996-06-19 | — | — | EP | disclosed |
| WO-1996000656-A1 | PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER | ELF ATOCHEM S.A. (FR) | 1996-01-11 | — | — | WO | disclosed |
| US-5470616-A | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0604677-A1 | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-4749727-A | THREE-DIMENSIONAL CROSSLINKING; EPOXIDES, UNSATURATED ALKOXYSILANES; WATER CURABLE | KANSAI PAINT CO., LTD. (JP) | 1988-06-07 | — | — | US | disclosed |
| US-4081421-A | Curable resin composition for abrasion-resistant coating | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1978-03-28 | — | — | US | disclosed |
| US-4029842-A | POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-06-14 | — | — | US | disclosed |