Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410792 | 0.69 | ALDH1A1 (0.52) | — | |
| SCHEMBL20189663 | 0.67 | PDE2A (0.33) | PDE2A | |
| SCHEMBL18075327 | 0.67 | PDE2A (0.44) | PDE2A | |
| SCHEMBL18075325 | 0.67 | PDE2A (0.44) | PDE2A | |
| SCHEMBL20189661 | 0.67 | PDE2A (0.33) | PDE2A | |
| SCHEMBL13359312 | 0.67 | NPSR1 (0.36) | PDE2A | |
| SCHEMBL1188746 | 0.65 | — | — | |
| SCHEMBL1187131 | 0.65 | — | — | |
| SCHEMBL14410874 | 0.65 | TLR8 (0.31) | PDE2A | |
| SCHEMBL7520889 | 0.65 | CDK1 (0.31) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992621-A1 | Heteroarylamide-substituted pyrimidone derivatives for the treatment of neurodegenerative diseases | Sanofi-Aventis (FR) | 2008-11-19 | — | — | EP | disclosed |