SCHEMBL8460922

SCHEMBL8460922

COC(OC)(C(C#N)(N(C(C)C)C(C)C)C(c1ccccc1)(c1ccccc1)c1ccccc1)P(O)(O)(O)CCCn1ccc(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8460047 0.87 TK2 (0.45)
SCHEMBL8458386 0.84
SCHEMBL8458487 0.78 LTA4H (0.37)
SCHEMBL8460546 0.74 TAAR1 (0.35)
SCHEMBL8459849 0.73
SCHEMBL8458624 0.73 TAAR1 (0.34)
SCHEMBL8461363 0.72
SCHEMBL7143879 0.68 DUT (0.38) DUT
SCHEMBL7144701 0.65 DUT (0.52) DUT
SCHEMBL13539814 0.62 DUT (0.68) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886177-A ETHYLENE GLYCOL MONOMERS JOINED VIA STANDARD PHOSPHATE LINKAGES INCLUDING PHOSPHOROTHIOATE, PHOSPHODIESTER, AND PHOSPHORAMIDATE LINKAGES; USEFUL FUNCTIONAL GROUPS INCLUDE NUCLEOBASES AS WELL AS POLAR GROUPS, HYDROPHOBIC GROUPS ISIS PHARMACEUTICALS, INC. (US) 1999-03-23 US disclosed