Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458386 | 0.80 | — | — | |
| SCHEMBL8460922 | 0.78 | DUT (0.42) | — | |
| SCHEMBL8460047 | 0.76 | TK2 (0.45) | — | |
| SCHEMBL8460546 | 0.74 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL8458624 | 0.73 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL7140650 | 0.71 | LTA4H (0.35) | LTA4HFDPS | |
| SCHEMBL8459849 | 0.68 | — | — | |
| SCHEMBL7149262 | 0.67 | FDPS (0.46) | LTA4HFDPS | |
| SCHEMBL8461363 | 0.67 | — | — | |
| SCHEMBL1742012 | 0.61 | FDPS (0.49) | LTA4HFDPSTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886177-A | ETHYLENE GLYCOL MONOMERS JOINED VIA STANDARD PHOSPHATE LINKAGES INCLUDING PHOSPHOROTHIOATE, PHOSPHODIESTER, AND PHOSPHORAMIDATE LINKAGES; USEFUL FUNCTIONAL GROUPS INCLUDE NUCLEOBASES AS WELL AS POLAR GROUPS, HYDROPHOBIC GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |