Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414452 | 0.84 | MCL1 (0.39) | HSD17B1TRPA1MCL1ALDH1A1TDP1 | |
| SCHEMBL5266651 | 0.82 | TRPA1 (0.36) | HSD17B1TRPA1MCL1ALDH1A1TDP1 | |
| SCHEMBL1451927 | 0.82 | MCL1 (0.46) | HSD17B1TRPA1MCL1TAS1R3TAS1R1 | |
| SCHEMBL17784933 | 0.79 | MCL1 (0.40) | HSD17B1TRPA1MCL1ALDH1A1TDP1 | |
| SCHEMBL28566020 | 0.79 | ALDH1A1 (0.42) | TRPA1MCL1ALDH1A1TDP1TP53 | |
| SCHEMBL29030408 | 0.78 | MCL1 (0.41) | HSD17B1TRPA1MCL1ALDH1A1TAS1R3 | |
| SCHEMBL29483331 | 0.77 | HSD17B1 (0.41) | HSD17B1ALDH1A1RXRARARARARB | |
| SCHEMBL20262941 | 0.77 | HSD17B1 (0.41) | HSD17B1ALDH1A1RXRARARARARB | |
| SCHEMBL14321375 | 0.77 | MCL1 (0.55) | MCL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30767842 | 0.77 | TDP1 (0.45) | TRPA1MCL1ALDH1A1TDP1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700963-B1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | claimed |
| WO-2023015283-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS | CELGENE CORPORATION (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-0117831-A1 | Stabilized polyester compositions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |