Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL36961 | 0.95 | CHRNB2 (0.40) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL8460212 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL8460504 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL7635178 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL8460511 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL3909243 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL8460505 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL9332259 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL1271620 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 | |
| Tetramethylammonium Ion SCHEMBL8461568 | 0.91 | BBOX1 (0.36) | BBOX1CHRNB2CHRNA7CHRNA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863838-A | Method for chemically-mechanically polishing a metal layer | MOTOROLA, INC. (US) | 1999-01-26 | — | — | US | disclosed |