SCHEMBL8461574

SCHEMBL8461574

CC=CC(=O)OCC[SiH2]C(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 4/20 0.34
GSTP1 P09211 1/20 0.32
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL341121 0.90 ATM (0.42) ATMHCAR2GSTP1LMNA
SCHEMBL28074015 0.89 ATM (0.41) ATMHCAR2GSTP1
SCHEMBL21291808 0.87 HCAR2 (0.41) ATMHCAR2
SCHEMBL733860 0.81 TSHR (0.47)
SCHEMBL3917255 0.75 ATM (0.38) ATMHCAR2
SCHEMBL8673805 0.74 ATM (0.52) ATMHCAR2GSTP1
SCHEMBL21636771 0.74 ATM (0.52) ATMHCAR2GSTP1
SCHEMBL27716011 0.74 ATM (0.52) ATMHCAR2GSTP1
SCHEMBL35613 0.74 ATM (0.40) ATMHCAR2
SCHEMBL15402551 0.74 ATM (0.40) ATMHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
US-11634574-B2 Rubber-containing graft polymer, resin composition containing rubber-containing graft polymer, and shaped article of same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-04-25 US disclosed
EP-3375800-B1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER MITSUBISHI CHEM CORP (JP) 2021-07-07 EP disclosed
US-20200299502-A1 RUBBER-CONTAINING GRAFT POLYMER, RESIN COMPOSITION CONTAINING RUBBER-CONTAINING GRAFT POLYMER, AND SHAPED ARTICLE OF SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2020-09-24 US disclosed
EP-3034532-B1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER MITSUBISHI CHEM CORP (JP) 2019-11-06 EP disclosed
US-10246585-B2 Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded product MITSUBISHI CHEMICAL CORPORATION (JP) 2019-04-02 US disclosed
EP-3015484-B1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE MITSUBISHI CHEM CORP (JP) 2018-10-24 EP disclosed
EP-3375800-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER Mitsubishi Chemical Corporation (JP) 2018-09-19 EP disclosed
US-20180127579-A1 Polyorganosiloxane-Containing Graft Copolymer, Thermoplastic Resin Composition, and Molded Product MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-10 US disclosed
US-20160194428-A1 GRAFT COPOLYMER CONTAINING POLYORGANOSILOXANE, RESIN COMPOSITION, MOLDED ARTICLE, SLIDABILITY-IMPROVING AGENT, AND SLIDING MEMBER MITSUBISHI RAYON CO., LTD. (JP) 2016-07-07 US disclosed
EP-3034532-A2 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER Mitsubishi Rayon Co., Ltd. (JP) 2016-06-22 EP disclosed
US-20160137836-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED PRODUCT MITSUBISHI RAYON CO., LTD. (JP) 2016-05-19 US disclosed
EP-3015484-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE Mitsubishi Rayon Co., Ltd. (JP) 2016-05-04 EP disclosed
US-20150267048-A1 Polyorganosiloxane-Containing Graft Copolymer, Resin Composition, and Molded Article MITSUBISHI RAYON CO., LTD. (JP) 2015-09-24 US disclosed
EP-0928302-A1 NEW POLYMER COMPOSITIONS, GRAFT COPOLYMERS AND THERMOPLASTIC COMPOUNDS WITH CROSS-LINKING GRADIENTS MADE OF SUCH COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1999-07-14 EP disclosed
WO-1999015577-A1 METHOD FOR PRODUCING A CROSS-LINKED POLYMER COMPOSITION WITH COLORING AGENTS FOR ELECTROPHOTOGRAPHIC TONER BASF AKTIENGESELLSCHAFT (DE) 1999-04-01 WO disclosed
WO-1998013403-A1 NEW POLYMER COMPOSITIONS, GRAFT COPOLYMERS AND THERMOPLASTIC COMPOUNDS WITH CROSS-LINKING GRADIENTS MADE OF SUCH COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1998-04-02 WO disclosed
US-5280054-A Blend of water dispersible silica, polymerizable vinylsilane, unsaturated monomer, curing agent and hydroxyl group containing polyester MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1994-01-18 US disclosed
EP-0307963-A2 Polycarbonate resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-22 EP disclosed