SCHEMBL949699

SCHEMBL949699

C=CC(=O)OCCCO[Si](CCC)(OCCC)OCCC

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
HPGD P15428 1/20 0.59
ALDH1A1 P00352 5/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
ATM Q13315 1/20 0.41
THRB P10828 3/20 0.40
HCAR2 Q8TDS4 4/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL949700 0.90 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29850335 0.89 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8461591 0.87 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL4249650 0.86 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL136294 0.86 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4TP53
Dimethylamine SCHEMBL28428936 0.84 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8458247 0.84 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28471216 0.83 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28563625 0.83 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28013523 0.83 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013740-B2 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORP (JP) 2011-01-19 EP disclosed
US-7871713-B2 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2011-01-18 US disclosed
US-7316851-B2 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2008-01-08 US disclosed
US-7264890-B2 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2007-09-04 US disclosed
EP-1764401-A1 Electroluminescent material and electroluminescent element KONICA CORPORATION (JP) 2007-03-21 EP disclosed
US-20070020485-A1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2007-01-25 US disclosed
EP-1731585-A2 Electroluminescent material and electroluminescent element Konica Corporation (JP) 2006-12-13 EP disclosed
EP-1731586-A2 Electroluminescent material and electroluminescent element Konica Corporation (JP) 2006-12-13 EP disclosed
EP-1013740-B1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORP (JP) 2006-10-11 EP disclosed
US-20040096696-A1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2004-05-20 US disclosed
US-20040072019-A1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2004-04-15 US disclosed
US-20040062951-A1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2004-04-01 US disclosed
US-20040058195-A1 For use in civil or industrial displaying device such as a light- emission type multi- or full-color display, or a displaying panel, and color image forming KONICA CORPORATION (JP) 2004-03-25 US disclosed
US-6656608-B1 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2003-12-02 US disclosed
EP-1013740-A2 Electroluminescent material, electroluminescent element and color conversion filter KONICA CORPORATION (JP) 2000-06-28 EP disclosed