Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425927 | 0.84 | ALDH1A1 (0.50) | ALDH1A1BCHEKDM4E | |
| SCHEMBL18605401 | 0.78 | ALDH1A1 (0.44) | ALDH1A1BCHEMETAP2 | |
| SCHEMBL6671627 | 0.76 | BCHE (0.49) | ALDH1A1BCHEPSEN1PSEN2APH1B | |
| SCHEMBL8462364 | 0.76 | ALDH1A1 (0.41) | ALDH1A1BCHEHCRTR2PSEN1PSEN2 | |
| SCHEMBL8462362 | 0.76 | ALDH1A1 (0.41) | ALDH1A1BCHEHCRTR2PSEN1PSEN2 | |
| SCHEMBL31756156 | 0.75 | ALDH1A1 (0.41) | ALDH1A1BCHEMETAP2 | |
| SCHEMBL12573457 | 0.73 | LMNA (0.47) | ALDH1A1BCHEHCRTR2 | |
| SCHEMBL12573446 | 0.73 | PDE4D (0.43) | ALDH1A1BCHE | |
| SCHEMBL24898573 | 0.73 | PDE4D (0.49) | ALDH1A1BCHEHCRTR2PSEN1PSEN2 | |
| SCHEMBL21872714 | 0.73 | PDE4D (0.49) | ALDH1A1BCHEHCRTR2PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | claimed |
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5886233-A | Cyclohexanone derivatives, process for their production and intermediate products of the process | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |