Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462047 | 0.84 | PGK1 (0.42) | EPHX2PDE2APGK1GRIA1CACNG8 | |
| SCHEMBL8461786 | 0.83 | — | — | |
| SCHEMBL7931554 | 0.76 | EPAS1 (0.42) | EPHX2PDE2A | |
| SCHEMBL3137556 | 0.76 | TSHR (0.42) | PGK1GRIN2BNOTUMKMO | |
| SCHEMBL8074938 | 0.76 | GAA (0.42) | PGK1GRIA1CACNG8GRIN2BSLC1A5 | |
| SCHEMBL25244745 | 0.75 | ALDH1A1 (0.33) | EPHX2PDE2APGK1GRIA1CACNG8 | |
| SCHEMBL25789745 | 0.75 | P2RX7 (0.37) | EPHX2PDE2APGK1GRIA1CACNG8 | |
| SCHEMBL25244315 | 0.75 | GAA (0.34) | EPHX2PDE2APGK1GRIA1CACNG8 | |
| SCHEMBL8396955 | 0.74 | EPHX2 (0.50) | EPHX2PDE2A | |
| SCHEMBL23389167 | 0.73 | PDE2A (0.41) | EPHX2PDE2APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981789-A | CHLORODENITRATING AROMATIC COMPOUNDS USING LESS CHLORINATING AGENT AND LOWER TEMPERATURES, THEN RECYCLING THE PRODUCT MIXTURE TO INCREASE THE YIELD | OCCIDENTAL CHEMICAL CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| US-4704483-A | FLUORINATION WITH POTASSIUM FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4582948-A | VAPOR PHASE CHLORO-DENITRATION REACTION | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |