Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565865 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL28493002 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL15440287 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL8463268 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1RXRALCKTDP1 | |
| SCHEMBL31355236 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL8464799 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL15989607 | 0.75 | LCK (0.52) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL664622 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2CDC25BKDM4EPOLBAKR1C3 | |
| SCHEMBL8462552 | 0.74 | CA12 (0.55) | KDM4EALDH1A1HPGDCA1CA2 | |
| SCHEMBL8460400 | 0.74 | CA1 (0.46) | SMN1; SMN2CDC25BKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |