Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461083 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL383820 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL8463004 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL29853676 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL7267474 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL8460483 | 0.77 | CA12 (0.57) | POLBALDH1A1LMNAMAPTMEN1 | |
| Benzene SCHEMBL29227606 | 0.77 | ALDH1A1 (0.63) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL8463843 | 0.77 | PTPN11 (0.45) | SMN1; SMN2ALDH1A1CA1GAACA12 | |
| SCHEMBL5307872 | 0.76 | NPC1 (0.63) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL8462433 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |