SCHEMBL580975

SCHEMBL580975

CC1(C)CC(OC(=O)CCC(=O)OC2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.45
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 4/20 0.35
EPHX1 P07099 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 2/20 0.34
ESR1 P03372 1/20 0.34
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
CYP19A1 P11511 2/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.32
EPHX2 P34913 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9040342 0.94 NAAA (0.41) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL453206 0.94 NAAA (0.54) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL9743615 0.93 NAAA (0.56) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL10467609 0.93 NAAA (0.56) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL30894534 0.93 NAAA (0.56) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL698203 0.93 NAAA (0.56) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL9195976 0.92 NAAA (0.41) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL30894533 0.91 NAAA (0.55) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL13412654 0.91 CYP2C19 (0.40) NAAACYP2C19SMN1; SMN2HTTKMT2A
SCHEMBL19720356 0.89 NAAA (0.40) NAAACYP2C19SMN1; SMN2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677392-B2 USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-13 US claimed
US-6508847-B2 Discoloration inhibition; stability CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 US claimed
US-6472456-B1 POLYOLEFINS, ESPECIALLY POLYPROPYLENE, CAN BE MADE FLAME RETARDANT BY THE INCORPORATION THEREIN OF A SYNERGISTIC MIXTURE OF A SELECTED HINDERED AMINE SUBSTITUTED BY AN ALKOXY, CYDOALKOXY OR HYDROXYALKOXY MOIETY AND A SELECTED CIBA SPECIALTY CHEMICALS CORP. 2002-10-29 US claimed
US-20020115753-A1 Photostable, silylated benzotriazole UV absorbers and compositions stabilized therewith RAVICHANDRAN RAMANATHAN (US) 2002-08-22 US claimed
US-20020111404-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith WOOD MERVIN (US) 2002-08-15 US claimed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP claimed
US-6380285-B1 AS ULTRAVIOLET RADIATION ABSORBERS WHILE NOT BLOOMING WHEN INCORPORATED INTO POLYOLEFIN FILMS CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-30 US claimed
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2001-09-20 US claimed
US-20010007886-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2001-07-12 US claimed
EP-0572554-B1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-05-10 EP claimed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US claimed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP claimed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP claimed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP claimed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US claimed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US claimed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111404-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith POLL, SCD, RAD51 NAAA 1180/4885CYP2C19 751/4885SMN1; SMN2 1915/4885
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith FAAH, DBF4, TPH1 NAAA 1026/4885CYP2C19 723/4885SMN1; SMN2 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.