Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067197 | 0.89 | TSHR (0.38) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL13412654 | 0.85 | CYP2C19 (0.40) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL8462829 | 0.84 | TSHR (0.49) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL10160344 | 0.84 | EPHX1 (0.46) | EPHX1TSHRGAA | |
| Hydrochloric Acid SCHEMBL9337013 | 0.82 | TSHR (0.35) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL580975 | 0.82 | NAAA (0.45) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL9270235 | 0.82 | TSHR (0.38) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL13474861 | 0.82 | TSHR (0.35) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL9270239 | 0.82 | TSHR (0.38) | EPHX1TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL9334232 | 0.82 | TSHR (0.35) | EPHX1TSHRKMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0647626-A1 | Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |
| US-5380828-A | Stabilization by being grafted onto a polymer | CIBA-GEIGY CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |