Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465761 | 0.92 | KMT2A (0.40) | KMT2AMEN1LMNAGAAPOLB | |
| Butadiene SCHEMBL8463302 | 0.89 | KMT2A (0.40) | KMT2AMEN1LMNAGAAPOLB | |
| SCHEMBL8466872 | 0.88 | MEN1 (0.37) | KMT2AMEN1LMNAGAAPOLB | |
| SCHEMBL8463296 | 0.77 | CYP2C19 (0.41) | KMT2ALMNAALDH1A1HPGDHTT | |
| SCHEMBL8465654 | 0.77 | MEN1 (0.33) | KMT2AMEN1LMNAGAAPOLB | |
| SCHEMBL8466034 | 0.76 | POLB (0.35) | KMT2AMEN1LMNAPOLBHDAC3 | |
| SCHEMBL8522938 | 0.76 | POLB (0.33) | KMT2APOLBHDAC3HDAC7HDAC8 | |
| SCHEMBL8465641 | 0.74 | HPGD (0.40) | LMNAGAAALDH1A1HPGDHTT | |
| SCHEMBL8579545 | 0.70 | ALDH1A1 (0.32) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL8679027 | 0.69 | MEN1 (0.39) | KMT2AMEN1LMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767795-B1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5770538-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0767795-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5539068-A | Group 4, metal-conjugated diene metallocyclopentene complexes, and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5486632-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1996000734-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |