Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463296 | 0.90 | CYP2C19 (0.41) | HPGDCYP2C19SMN1; SMN2ALDH1A1HTT | |
| Butadiene SCHEMBL8463476 | 0.87 | CYP2C19 (0.41) | HPGDCYP2C19SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8463320 | 0.86 | CYP2C19 (0.39) | HPGDCYP2C19SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8465761 | 0.82 | KMT2A (0.40) | HPGDCYP2C19ALDH1A1GAAHTT | |
| SCHEMBL8462546 | 0.81 | HPGD (0.37) | HPGDCYP2C19KCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL7743272 | 0.80 | CYP2C19 (0.41) | HPGDCYP2C19SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8008148 | 0.80 | CYP2C19 (0.41) | HPGDCYP2C19SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6471494 | 0.76 | KMT2A (0.38) | HPGDCYP2C19SMN1; SMN2RAB9AHDAC1 | |
| SCHEMBL8465295 | 0.75 | ALDH1A1 (0.37) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL8678494 | 0.75 | ALDH1A1 (0.37) | HPGDCYP2C19KCNK3KCNK9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767795-B1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5770538-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0767795-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5539068-A | Group 4, metal-conjugated diene metallocyclopentene complexes, and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5486632-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1996000734-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |