Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464024 | 0.81 | CDC25B (0.47) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8464392 | 0.80 | KDM4E (0.44) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8459358 | 0.80 | PRNP (0.53) | ALDH1A1KMT2AKDM4EMEN1RXFP1 | |
| SCHEMBL8464827 | 0.80 | ALB (0.44) | ALDH1A1NR4A2NR4A1NR4A3WDR5 | |
| SCHEMBL8460585 | 0.79 | HNF4A (0.49) | ALDH1A1KDM4EMAPTHPGDNR4A2 | |
| SCHEMBL10583391 | 0.77 | KDM4E (0.66) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8463827 | 0.76 | TTR (0.46) | HSD17B10CYP1A2NR4A2NR4A1NR4A3 | |
| SCHEMBL8460917 | 0.76 | CDC25B (0.52) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8460730 | 0.76 | TAS2R14 (0.40) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL4098387 | 0.76 | TSHR (0.63) | TSHRALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |