⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL28321133 | 1.00 | TSHR (0.40) | — | |
| Chloroform SCHEMBL27836013 | 0.95 | ALDH1A1 (0.38) | — | |
| Methylene Chloride SCHEMBL1832445 | 0.84 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL9625167 | 0.84 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL992285 | 0.84 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL7090995 | 0.84 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL4933917 | 0.84 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL292514 | 0.84 | ALDH1A1 (0.57) | — | |
| Chloroform SCHEMBL258696 | 0.84 | — | — | |
| Chloroform SCHEMBL9525441 | 0.84 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910080-A | Novel erlotinib-related substance and preparation method thereof | UNIV DALIAN TECH | 2015-09-16 | — | — | CN | claimed |
| CN-115778904-A | A preparation for in vitro transfection and in vivo mRNA delivery | 珠海丽凡达生物技术有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-10961202-B2 | Bis-benzimidazole compounds and methods of using the same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-03-30 | — | — | US | disclosed |
| CN-110638759-A | A preparation for in vitro transfection and in vivo mRNA delivery | 珠海丽凡达生物技术有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110452211-A | The extraction separation method and purposes of 2 noval chemical compounds in root of Japanese banana | UNIV GUIZHOU MEDICAL | 2019-11-15 | — | — | CN | disclosed |
| CN-104910080-B | A kind of Tarceva related substances and preparation method thereof | 大连理工大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-107075538-A | Strain of the class Nematomyces for the production of docosahexaenoic acid | 合成基因组股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104910080-A | Novel erlotinib-related substance and preparation method thereof | UNIV DALIAN TECH | 2015-09-16 | — | — | CN | disclosed |
| US-8497090-B2 | Fungal strains and a process for production of insecticide thereof | INDIAN INSTITUTE OF SCIENCE (IN) | 2013-07-30 | — | — | US | disclosed |
| US-8338450-B2 | Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors | LUPIN LIMITED (IN) | 2012-12-25 | — | — | US | disclosed |
| CN-1699313-A | Process for recovering methylene dichloride from multi-component mixed solution containing methylene dichloride | UNIV EAST CHINA SCIENCE & TECH (CN) | 2005-11-23 | — | — | CN | disclosed |
| US-6605618-B2 | Antidiabetic agents; hypoglycemic agents; anticholesterol agents; side effect reduction | WYETH | 2003-08-12 | — | — | US | disclosed |
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
| US-6451814-B1 | SUBSTITUTED 4-((4-AMINO-5-HYDROXYPHENYL)-OXY-)PIPERIDINE ANALOGS; METABOLIC DISORDERS; ANTIDIABETIC AGENTS; ATHERO-SCLEROSIS, GASTROINTESTINAL DISORDERS, GLAUCOMA, NEUROGENETIC INFLAMMATION, OCULAR HYPERTENSION AND FREQUENT URINATION | WYETH | 2002-09-17 | — | — | US | disclosed |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-07 | — | — | US | disclosed |
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
| EP-0419567-A1 | PROCESS FOR INDUCING CYTOCHROME P-450 ENZYMES IN STREPTOMYCES-BACTERIA AND DETERMINING THE MUTAGENICITY OF CHEMICALS. | DU PONT (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1989012686-A1 | PROCESS FOR INDUCING CYTOCHROME P-450 ENZYMES IN STREPTOMYCES BACTERIA AND DETERMINING THE MUTAGENICITY OF CHEMICALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-28 | — | — | WO | disclosed |
| US-4021441-A | 1-[(Allylamino)-methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines | THE UPJOHN COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-4010177-A | [3-Substituted-5-[(di-methylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenones and process | THE UPJOHN COMPANY (US) | 1977-03-01 | — | — | US | disclosed |