SCHEMBL8464205

SCHEMBL8464205

CONC(=O)N(C)c1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
ALOX5 P09917 1/20 0.32
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
POLB P06746 1/20 0.31
CYP26B1 Q9NR63 1/20 0.31
PPARG P37231 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390499 0.80 MEN1 (0.43) RXRARXRBRXRGMEN1KMT2A
SCHEMBL67099 0.80 MEN1 (0.43) RXRARXRBRXRGMEN1KMT2A
SCHEMBL9749135 0.80 ALDH1A1 (0.44) RXRARXRBRXRGMAPTMEN1
SCHEMBL9754850 0.78 MTNR1B (0.38) RXRARXRBRXRGMAPTMEN1
Metobromuron SCHEMBL15994323 0.77 KMT2A (0.52) RXRARXRBRXRGMAPTMEN1
SCHEMBL9748606 0.76 ALDH1A1 (0.41) MAPTMEN1ALDH1A1LMNAHTT
SCHEMBL9754845 0.74 RXRA (0.33) RXRARXRBRXRG
SCHEMBL9847651 0.71 MEN1 (0.40) MEN1KMT2APOLB
SCHEMBL9847576 0.71 MEN1 (0.40) ALOX5MEN1ALDH1A1KMT2A
SCHEMBL9847560 0.70 MEN1 (0.38) ALOX5MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990044-A Selective herbicides based on aryl uracils BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US claimed