Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL846422

CN(C)CCCN1CN(CCCN(C)C)CN(CCCN(C)C)C1.N

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 2/20 0.43
ALOX15 P16050 1/20 0.41
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
CYP2D6 P10635 3/20 0.37
HRH2 P25021 3/20 0.37
SLC22A1 O15245 2/20 0.37
PRNP P04156 2/20 0.37
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
HTR1A P08908 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
DRD2 P14416 2/20 0.37
ADRA2B P18089 2/20 0.37
ADRA2C P18825 2/20 0.37
CHRM3 P20309 2/20 0.37
DRD1 P21728 2/20 0.37
DRD4 P21917 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232543 0.97 ALDH1A1 (0.45) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL28036482 0.95 ALDH1A1 (0.43) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL9551161 0.88 ALDH1A1 (0.38) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL9551187 0.88 DNM1 (0.48) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL15334615 0.88 ALDH1A1 (0.38) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL20927226 0.86 ALOX15 (0.37) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL11438621 0.86 MAPT (0.40) ALDH1A1TSHRALOX15LMNAMAPT
SCHEMBL9551177 0.84 DNM1 (0.56) ALDH1A1TSHRCYP2D6DNM1CYP1A2
SCHEMBL9551167 0.84 DNM1 (0.56) ALDH1A1TSHRCYP2D6DNM1CYP1A2
SCHEMBL6379727 0.84 DNM1 (0.56) ALDH1A1TSHRCYP2D6DNM1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905707-B2 Foam wall structures and methods for their manufacture COVESTRO LLC (US) 2024-02-20 US disclosed
US-20220412080-A1 HFO-CONTAINING ISOCYANATE-REACTIVE COMPOSITIONS, RELATED POLYURETHANE FOAM-FORMING COMPOSITIONS, AND SPRAY-APPLIED POLYURETHANE FOAMS COVESTRO LLC 2022-12-29 US disclosed
US-20220412081-A1 FOAM WALL STRUCTURES AND METHODS FOR THEIR MANUFACTURE COVESTRO LLC 2022-12-29 US disclosed
EP-1802689-B1 BLOWING AGENT COMPOSITION AND POLYISOCYANATE-BASED FOAM PRODUCED THEREWITH DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-28 EP disclosed
US-20080096994-A1 Blowing Agent Composition and Polyisocyanate-Based Foam Produced Therewith SNIDER DAVID E 2008-04-24 US disclosed
EP-1802689-A1 BLOWING AGENT COMPOSITION AND POLYISOCYANATE-BASED FOAM PRODUCED THEREWITH Dow Gloval Technologies Inc. (US) 2007-07-04 EP disclosed
EP-1597300-B1 ROCESS FOR PREPARING AMINE-INITIATED POLYETHER POLYOLS BAYER MATERIALSCIENCE LLC (US) 2006-09-27 EP disclosed
WO-2006044304-A1 BLOWING AGENT COMPOSITION AND POLYISOCYANATE-BASED FOAM PRODUCED THEREWITH DOW GLOBAL TECHNOLOGIES INC. (US) 2006-04-27 WO disclosed
US-20040082675-A1 Rigid foams and a process for the production of such foams BAYER MATERIALSCIENCE LLC 2004-04-29 US disclosed