Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | MMP15 | P51511 | 1/20 | 0.30 |
| ▸ | MMP16 | P51512 | 1/20 | 0.30 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749056 | 0.79 | CA12 (0.38) | LMNA | |
| SCHEMBL7140092 | 0.68 | MTNR1A (0.39) | BCHE | |
| SCHEMBL6749065 | 0.68 | NPC1 (0.33) | LMNA | |
| SCHEMBL6747496 | 0.67 | TP53 (0.33) | LMNA | |
| SCHEMBL6749339 | 0.67 | FFAR1 (0.41) | LMNAPDE4AFFAR1 | |
| SCHEMBL6749047 | 0.66 | HTR2A (0.42) | — | |
| SCHEMBL11685677 | 0.63 | TNF (0.52) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6750211 | 0.62 | HDAC6 (0.36) | — | |
| SCHEMBL5484265 | 0.62 | LMNA (0.42) | LMNABCHE | |
| SCHEMBL11473821 | 0.59 | POLB (0.36) | MMP2MMP9MMP12MMP14MMP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |