Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460841 | 0.91 | TSHR (0.37) | TSHRAGBL2AKR1B1AKR1A1HSD17B10 | |
| SCHEMBL8464341 | 0.82 | POLB (0.50) | TSHRAKR1B1HSD17B10MEN1POLB | |
| SCHEMBL8464321 | 0.80 | KEAP1 (0.40) | AKR1B1HSD17B10CXCL8 | |
| SCHEMBL8463501 | 0.80 | AKR1B1 (0.36) | TSHRAKR1B1HSD17B10CXCL8MEN1 | |
| SCHEMBL8459629 | 0.80 | HPGD (0.44) | TSHRAKR1B1HSD17B10MEN1POLB | |
| SCHEMBL8462903 | 0.80 | AKR1B1 (0.36) | AKR1B1HSD17B10MEN1POLBKMT2A | |
| SCHEMBL8460216 | 0.77 | POLB (0.42) | AKR1B1HSD17B10RXRARXRBRXRG | |
| SCHEMBL8463402 | 0.77 | CXCL8 (0.34) | TSHRAKR1B1CXCL8MEN1KMT2A | |
| SCHEMBL8461777 | 0.76 | PTGS1 (0.57) | TSHRAKR1B1MEN1KMT2AMMP1 | |
| SCHEMBL8464523 | 0.76 | HSD17B10 (0.56) | HSD17B10RXRARXRBRXRGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |