Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460483 | 0.78 | CA12 (0.57) | MYCCES2MEN1KMT2APOLB | |
| SCHEMBL8464941 | 0.78 | KDM4E (0.48) | KDM4EMYCAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL618056 | 0.76 | KDM4E (0.65) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL8460406 | 0.76 | CSNK2A1 (0.57) | KDM4EAKR1C3MEN1KMT2APOLB | |
| SCHEMBL8464933 | 0.76 | ALDH1A1 (0.59) | KDM4EMYCNR4A1GPR35HPGD | |
| SCHEMBL8462809 | 0.76 | KEAP1 (0.55) | KDM4EHPGDCES2CYP2C19APEX1 | |
| SCHEMBL8464393 | 0.75 | ALDH1A1 (0.42) | KDM4EGLAHPGDCES2GALR3 | |
| SCHEMBL4441828 | 0.74 | KDM4E (0.63) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL30219515 | 0.74 | KDM4E (0.63) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL2482965 | 0.74 | KDM4E (0.63) | KDM4EGLAMYCNR4A1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |