SCHEMBL8464652

SCHEMBL8464652

CCN(C(=O)n1nnn(-c2ccccc2Cl)c1=O)C1CCCC1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
TSHR P16473 2/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.36
RAB9A P51151 1/20 0.36
PDE4B Q07343 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
CCR5 P51681 1/20 0.35
TRPM8 Q7Z2W7 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464654 1.00 L3MBTL1 (0.40) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL8904157 0.99 L3MBTL1 (0.42) L3MBTL1SLC6A2SLC6A4TSHRHPGD
Fentrazamide SCHEMBL116505 0.99 L3MBTL1 (0.42) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL8904153 0.99 L3MBTL1 (0.42) L3MBTL1SLC6A2SLC6A4TSHRHPGD
Fentrazamide SCHEMBL30750933 0.99 L3MBTL1 (0.42) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL8466641 0.92 DRD2 (0.41) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL8464533 0.92 DRD2 (0.41) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL12115886 0.91 DRD2 (0.44) L3MBTL1SLC6A2SLC6A4TSHRHPGD
SCHEMBL7980487 0.91 CNR1 (0.35) SLC6A2SLC6A4RAB9APDE4BMEN1
SCHEMBL12115702 0.91 DRD2 (0.42) L3MBTL1SLC6A2SLC6A4TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP claimed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US claimed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP claimed
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP disclosed
US-5833733-A SOLID CORE, COATING; FUNGICIDE, HERBICIDE, NUTRIENTS; FOR RICE PADDYS NIHON BAYER AGROCHEM K.K. (JP) 1998-11-10 US disclosed
EP-0612735-B1 1-(substituted phenyl) tetrazolinone derivatives, their preparation and their use as herbicides BAYER AGROCHEM KK (JP) 1998-05-13 EP disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP disclosed
US-5362704-A Herbicidal tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1994-11-08 US disclosed
EP-0612735-A1 1-(substituted phenyl) tetrazolinone derivatives, their preparation and their use as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-08-31 EP disclosed