Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464533 | 1.00 | DRD2 (0.41) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12115702 | 0.99 | DRD2 (0.42) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8464654 | 0.92 | L3MBTL1 (0.40) | SLC6A2SLC6A4HPGDTSHRPDE4B | |
| SCHEMBL8464652 | 0.92 | L3MBTL1 (0.40) | SLC6A2SLC6A4HPGDTSHRPDE4B | |
| SCHEMBL8904153 | 0.91 | L3MBTL1 (0.42) | DRD2DRD3SLC6A2SLC6A4HPGD | |
| Fentrazamide SCHEMBL116505 | 0.91 | L3MBTL1 (0.42) | DRD2DRD3SLC6A2SLC6A4HPGD | |
| SCHEMBL8904157 | 0.91 | L3MBTL1 (0.42) | DRD2DRD3SLC6A2SLC6A4HPGD | |
| Fentrazamide SCHEMBL30750933 | 0.91 | L3MBTL1 (0.42) | DRD2DRD3SLC6A2SLC6A4HPGD | |
| SCHEMBL8977192 | 0.90 | UBE2M (0.37) | DRD2DRD3P2RX1P2RX4PDE4B | |
| SCHEMBL8977194 | 0.90 | UBE2M (0.37) | DRD2DRD3P2RX1P2RX4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714602-B1 | Sulphonylaminophenyluracil herbicides for paddy field | BAYER AGROCHEM KK (JP) | 1999-05-12 | — | — | EP | claimed |
| US-5641725-A | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | claimed |
| EP-0714602-A1 | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1996-06-05 | — | — | EP | claimed |
| US-5362704-A | Herbicidal tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1994-11-08 | — | — | US | claimed |
| US-20170119734-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS, INC. | 2017-05-04 | — | — | US | disclosed |
| EP-3159331-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | Infinity Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2566853-B1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |
| US-9346769-B2 | Tetrazolones as inhibitors of fatty acid synthase | INFINITY PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140079667-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8546432-B2 | Tetrazolones as inhibitors of fatty acid synthase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110274655-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | Infinity Pharmaceuticals (US) | 2011-11-10 | — | — | US | disclosed |
| EP-0714602-B1 | Sulphonylaminophenyluracil herbicides for paddy field | BAYER AGROCHEM KK (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5833733-A | SOLID CORE, COATING; FUNGICIDE, HERBICIDE, NUTRIENTS; FOR RICE PADDYS | NIHON BAYER AGROCHEM K.K. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0612735-B1 | 1-(substituted phenyl) tetrazolinone derivatives, their preparation and their use as herbicides | BAYER AGROCHEM KK (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5641725-A | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714602-A1 | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5362704-A | Herbicidal tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0612735-A1 | 1-(substituted phenyl) tetrazolinone derivatives, their preparation and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274655-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | FASN, ACSL1, HSD17B12 | DRD2 4876/4885DRD3 4853/4885SLC6A2 4866/4885 |
| US-20170119734-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | FASN, ACSL1, HSD17B12 | DRD2 4877/4885DRD3 4853/4885SLC6A2 4867/4885 |
| US-20140079667-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | FASN, ACSL1, HSD17B12 | DRD2 4876/4885DRD3 4853/4885SLC6A2 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.