Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 5/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464656 | 1.00 | P2RX4 (0.48) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL9017169 | 0.93 | P2RX4 (0.45) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL9017165 | 0.93 | P2RX4 (0.45) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL18820796 | 0.91 | LMNA (0.40) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL8467356 | 0.90 | P2RX4 (0.50) | P2RX4P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL8467359 | 0.90 | P2RX4 (0.50) | P2RX4P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL12115975 | 0.88 | PDE4B (0.40) | P2RX4P2RX1SMN1; SMN2NPSR1PDE4B | |
| SCHEMBL6816570 | 0.86 | P2RX4 (0.50) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL6816393 | 0.86 | P2RX4 (0.50) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 | |
| SCHEMBL6816374 | 0.85 | P2RX4 (0.37) | P2RX4P2RX1PTBP1P2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714602-B1 | Sulphonylaminophenyluracil herbicides for paddy field | BAYER AGROCHEM KK (JP) | 1999-05-12 | — | — | EP | claimed |
| US-5641725-A | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | claimed |
| EP-0578090-B1 | Tetrazolinones as herbicides for use in a rice paddy | BAYER AGROCHEM KK (JP) | 1996-12-27 | — | — | EP | claimed |
| EP-0714602-A1 | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1996-06-05 | — | — | EP | claimed |
| US-5466660-A | Tetrazolinones as herbicides for use in paddy | NIHON BAYER AGROCHEM K.K. (JP) | 1995-11-14 | — | — | US | claimed |
| US-5347010-A | Tetrzolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-09-13 | — | — | US | claimed |
| EP-0578090-A2 | Tetrazolinones as herbicides for use in a rice paddy | NIHON BAYER AGROCHEM K.K. (JP) | 1994-01-12 | — | — | EP | claimed |
| JP-6199818-A | — | — | None | — | — | JP | disclosed |
| US-20170119734-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS, INC. | 2017-05-04 | — | — | US | disclosed |
| US-20170119734-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS, INC. | 2017-05-04 | — | — | US | disclosed |
| EP-3159331-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | Infinity Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2566853-B1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | INFINITY PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |
| US-9346769-B2 | Tetrazolones as inhibitors of fatty acid synthase | INFINITY PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-5641725-A | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0578090-B1 | Tetrazolinones as herbicides for use in a rice paddy | BAYER AGROCHEM KK (JP) | 1996-12-27 | — | — | EP | disclosed |
| EP-0714602-A1 | Sulphonylaminophenyluracil herbicides for paddy field | NIHON BAYER AGROCHEM K.K. (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5466660-A | Tetrazolinones as herbicides for use in paddy | NIHON BAYER AGROCHEM K.K. (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5347010-A | Tetrzolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-09-13 | — | — | US | disclosed |
| JP-H06199818-A | USE OF TETRAZOLINONES AS HERBICIDE FOR PADDY FIELD | NIPPON BAYERAGROCHEM KK | 1994-07-19 | — | — | JP | disclosed |
| EP-0578090-A2 | Tetrazolinones as herbicides for use in a rice paddy | NIHON BAYER AGROCHEM K.K. (JP) | 1994-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119734-A1 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE | FASN, ACSL1, HSD17B12 | P2RX4 4590/4885P2RX1 4063/4885PTBP1 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.