Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614051 | 0.83 | HDAC3 (0.55) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7614028 | 0.80 | ALDH1A1 (0.53) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7619460 | 0.72 | KDM4E (0.46) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7617774 | 0.72 | KDM4E (0.46) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7616376 | 0.69 | S1PR2 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7613532 | 0.69 | S1PR2 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8467642 | 0.69 | HDAC3 (0.48) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8817718 | 0.69 | HDAC3 (0.54) | KDM4EHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7619484 | 0.68 | PPARA (0.57) | MEN1KMT2A | |
| SCHEMBL682183 | 0.68 | HDAC3 (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |