Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.43 |
| ▸ | RXRG | P48443 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 9/20 | 0.43 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096516 | 0.78 | RXRA (0.52) | RXRARXRGRXRBAGBL2POLQ | |
| SCHEMBL8461706 | 0.76 | CES2 (0.43) | RXRARXRGRXRBGPR17CES2 | |
| SCHEMBL8462688 | 0.75 | RXRA (0.43) | RXRARXRGRXRBAGBL2POLQ | |
| SCHEMBL5574328 | 0.73 | CES2 (0.53) | RXRARXRGRXRBAGBL2POLQ | |
| SCHEMBL30716953 | 0.73 | POLQ (0.61) | RXRARXRGRXRBPOLQCES2 | |
| SCHEMBL3741058 | 0.73 | POLQ (0.61) | RXRARXRGRXRBPOLQCES2 | |
| SCHEMBL8460643 | 0.73 | RXRA (0.44) | RXRARXRGRXRBAGBL2POLQ | |
| SCHEMBL8462700 | 0.71 | TSHR (0.44) | RXRARXRGRXRBAGBL2 | |
| SCHEMBL7584232 | 0.70 | RXRA (0.39) | RXRARXRGRXRBAGBL2POLQ | |
| SCHEMBL8460438 | 0.69 | CES2 (0.36) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |