Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465447 | 0.82 | HSP90AA1 (0.47) | RAB9AALDH1A1GAANPC1HPGD | |
| SCHEMBL8465216 | 0.75 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465273 | 0.72 | HSP90AA1 (0.52) | KDM4ERAB9AALDH1A1GAANPC1 | |
| SCHEMBL8464752 | 0.72 | HSP90AA1 (0.59) | RAB9AALDH1A1GAANPC1HPGD | |
| SCHEMBL31237237 | 0.71 | HSP90AA1 (0.50) | KDM4ERAB9AALDH1A1GAANPC1 | |
| SCHEMBL8465101 | 0.71 | HSP90AA1 (0.50) | KDM4ERAB9AALDH1A1GAANPC1 | |
| SCHEMBL8466674 | 0.70 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465070 | 0.70 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL18347719 | 0.70 | CYP1A2 (0.50) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL11813953 | 0.68 | KDM4E (0.69) | KDM4ERAB9AALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | claimed |
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | disclosed |