Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445709 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL6437641 | 0.81 | TDP1 (0.35) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL11411854 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL3070052 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL6705528 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL1496295 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL30504752 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL5596220 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA2HPGDTDP1CA4 | |
| SCHEMBL1227488 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL7725837 | 0.74 | ALDH1A1 (0.77) | ALDH1A1CA2HPGDTDP1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874517-A | ADDITION OF PRIMARY PHENOLIC AND SECONDARY PHOSPHONITE ANTIOXIDANTS EITHER PRIOR TO OR AFTER THE POLYETHYLENE TEREPHTHALATE POLYCONDENSATION REACTION IN ORDER TO REDUCE THE AMOUNT OF REGENERATED ACETALDEHYDE PRODUCED | HOECHST CELANESE CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-4335039-A | DIOXANE PHOSPHITE STABILIZER | GENERAL ELECTRIC COMPANY (US) | 1982-06-15 | — | — | US | disclosed |