SCHEMBL6437641

SCHEMBL6437641

OP(O)c1ccccc1P(O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.35
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 4/20 0.35
CYP3A4 P08684 3/20 0.35
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA14 Q9ULX7 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALOX15 P16050 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
GMNN O75496 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2474597 0.83 MEN1 (0.33) TDP1ALDH1A1HSD17B10CYP3A4CA12
SCHEMBL13406819 0.81 TSHR (0.50) ALDH1A1LMNAPOLBIDO1CYP2A6
SCHEMBL29445709 0.81 ALDH1A1 (0.50) TDP1ALDH1A1HSD17B10CYP3A4CA12
SCHEMBL8465255 0.81 ALDH1A1 (0.50) TDP1ALDH1A1HSD17B10CYP3A4CA12
SCHEMBL3818763 0.78 ACHE (0.47) TDP1ALDH1A1CYP3A4CA2NPC1
SCHEMBL12620592 0.78 CES2 (0.39) TDP1ALDH1A1SMN1; SMN2ALOX15NPC1
SCHEMBL8386758 0.78 CYP3A4 (0.47) TDP1ALDH1A1HSD17B10CYP3A4SMN1; SMN2
SCHEMBL2127015 0.74 CYP1A2 (0.48) TDP1ALDH1A1HSD17B10CYP3A4ALOX15
SCHEMBL3757327 0.74 ALDH1A1 (0.48) TDP1ALDH1A1HSD17B10SMN1; SMN2POLB
SCHEMBL30753793 0.74 ALDH1A1 (0.48) TDP1ALDH1A1HSD17B10SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0151327-B1 STABILIZED COMPOSITIONS BASED ON ALPHA-OLEFIN POLYMERS SOLVAY & Cie (Société Anonyme) (BE) 1991-10-23 EP claimed
US-20050209359-A1 Use of antioxidants in radiation-curable coating compositions for producing adhesive coatings GOLDSCHMIDT AG 2005-09-22 US disclosed
EP-1303563-A1 MIXTURES OF PHOSPHORUS-CONTAINING COMPOUNDS USED AS POLYMER STABILISERS Clariant Finance (BVI) Limited (VG) 2003-04-23 EP disclosed
WO-2002006390-A1 MIXTURES OF PHOSPHORUS-CONTAINING COMPOUNDS USED AS POLYMER STABILIZERS CLARIANT FINANCE (BVI) LIMITED (VG) 2002-01-24 WO disclosed