Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HBB | P68871 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926305 | 0.87 | HSD17B10 (0.61) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9583133 | 0.82 | ALDH1A1 (0.53) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL11001414 | 0.81 | HSD17B10 (0.47) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL8466744 | 0.81 | KDM4E (0.47) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL10648298 | 0.80 | HDAC6 (0.47) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL10997884 | 0.80 | ALDH1A1 (0.50) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| Desciclovir SCHEMBL29403096 | 0.79 | PNP (0.52) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| Desciclovir SCHEMBL2028 | 0.79 | PNP (0.52) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL10650936 | 0.78 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL11001378 | 0.77 | HSD17B10 (0.46) | HSD17B10KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158513-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-16 | — | — | EP | claimed |
| US-5877163-A | TREATING AIDS WITH 3'-AZIDO-3'-DEOXYTHYMIDINE IN COMBINATION WITH INTERLEUKIN II OR PHOSPHONOFORMATE | GLAXO WELLCOME INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5683990-A | ADMINISTERING AZT AND 2-AMINO-9-(2-HYDROXYETHOXYMETHYL) PURINE IN TREATMENT OF AIDS | GLAXO WELLCOME INC. (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0158513-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-16 | — | — | EP | disclosed |