Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 6/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001414 | 0.86 | HSD17B10 (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8926305 | 0.83 | HSD17B10 (0.61) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9583275 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9582923 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8465302 | 0.81 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9182620 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8840050 | 0.79 | HSD17B10 (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10996278 | 0.79 | HSD17B10 (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8449563 | 0.77 | PDE3A (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8448373 | 0.77 | PDE3A (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158513-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-16 | — | — | EP | claimed |
| US-5877163-A | TREATING AIDS WITH 3'-AZIDO-3'-DEOXYTHYMIDINE IN COMBINATION WITH INTERLEUKIN II OR PHOSPHONOFORMATE | GLAXO WELLCOME INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5683990-A | ADMINISTERING AZT AND 2-AMINO-9-(2-HYDROXYETHOXYMETHYL) PURINE IN TREATMENT OF AIDS | GLAXO WELLCOME INC. (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0158513-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-16 | — | — | EP | disclosed |