Tert-Butanol

Tert-Butanol

SCHEMBL8465422

CC(C)(C)O.N.Nc1nc(N)nc(N)n1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
HSP90AA1 P07900 2/20 0.35
CASP1 P29466 1/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B10 Q99714 1/20 0.33
HSP90AB1 P08238 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31
NUDT1 P36639 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL1535535 0.78 LMNA (0.53) LMNAKDM4EGAAMAPTNPC1
Methyl Alcohol SCHEMBL11594237 0.78 LMNA (0.53) LMNAKDM4EGAAMAPTNPC1
Methyl Alcohol SCHEMBL8093100 0.78 LMNA (0.53) LMNAKDM4EGAAMAPTNPC1
Methyl Alcohol SCHEMBL7168433 0.78 LMNA (0.53) LMNAKDM4EGAAMAPTNPC1
Ammonia Solution, Strong SCHEMBL302019 0.78 CASP1 (0.47) LMNAKDM4EGAAMAPTNPC1
Ammonia Solution, Strong SCHEMBL3661841 0.78 CASP1 (0.47) LMNAKDM4EGAAMAPTNPC1
SCHEMBL14764506 0.77 HSD17B10 (0.42) LMNAKDM4EGAAMAPTNPC1
Hydrogen Peroxide SCHEMBL6095945 0.73 CYP1A2 (0.50) LMNAKDM4ENPC1RAB9AL3MBTL1
Bromide SCHEMBL28496993 0.73 CASP1 (0.44) LMNAKDM4EGAAMAPTNPC1
Hydroxyamine SCHEMBL8577072 0.73 LMNA (0.47) LMNAKDM4EGAAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5977258-A CLEAR COATS FOR CARS BOLLIG & KEMPER KG (DE) 1999-11-02 US disclosed