SCHEMBL14764506

SCHEMBL14764506

COC(C)(O)OC.Nc1nc(N)nc(N)n1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.37
NPC1 O15118 3/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
HSP90AA1 P07900 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
NUDT1 P36639 2/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27809111 0.83 HSD17B10 (0.40) HSD17B10LMNANPC1KDM4EGAA
SCHEMBL3732334 0.81 HSD17B10 (0.39) HSD17B10LMNANPC1KDM4EGAA
SCHEMBL9446120 0.78 HSD17B10 (0.38) HSD17B10LMNANPC1KDM4EGAA
Tert-Butanol SCHEMBL8465422 0.77 LMNA (0.43) HSD17B10LMNANPC1KDM4EGAA
SCHEMBL180902 0.76
SCHEMBL5804830 0.75 HSD17B10 (0.36) HSD17B10LMNAMAPT
SCHEMBL20508241 0.75 HSD17B10 (0.41) HSD17B10LMNANPC1KDM4EGAA
SCHEMBL9446118 0.73 HSD17B10 (0.35) HSD17B10LMNA
Methoxymethane SCHEMBL108410 0.73 LMNA (0.43) HSD17B10LMNANPC1KDM4EGAA
SCHEMBL27647833 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626351-B2 Treatment compositions THE PROCTER & GAMBLE COMPANY (US) 2020-04-21 US claimed
EP-2756067-B1 MICROCAPSULE COMPOSITIONS COMPRISING PH TUNEABLE DI-AMIDO GELLANTS PROCTER & GAMBLE (US) 2017-06-14 EP claimed
EP-2756067-A1 MICROCAPSULE COMPOSITIONS COMPRISING PH TUNEABLE DI-AMIDO GELLANTS The Procter & Gamble Company (US) 2014-07-23 EP claimed
US-20130303427-A1 MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS THE PROCTER & GAMBLE COMPANY 2013-11-14 US claimed
WO-2013039963-A1 MICROCAPSULE COMPOSITIONS COMPRISING PH TUNEABLE DI-AMIDO GELLANTS THE PROCTER & GAMBLE COMPANY (US) 2013-03-21 WO claimed
US-11999843-B2 Polyvinyl alcohol compositions with eutectic solvents, articles thereof, and methods of making same THE PROCTER & GAMBLE COMPANY (US) 2024-06-04 US disclosed
EP-3575339-B1 DRYER SHEETS COMPRISING BRANCHED POLYESTER POLYMERS PROCTER & GAMBLE (US) 2024-05-08 EP disclosed
EP-4362705-A1 SPRAY NOZZLE FOR DISPENSING A STRUCTURED COMPOSITION AND A SPRAY PRODUCT COMPRISING THE SAME The Procter & Gamble Company (US) 2024-05-08 EP disclosed
US-11925733-B2 Malodor counteractant composition and methods BELL FLAVORS & FRAGRANCES, INC. (US) 2024-03-12 US disclosed
US-20240060016-A1 Low-Water Compositions THE PROCTER & GAMBLE COMPANY 2024-02-22 US disclosed
US-20240060015-A1 SOLID DISSOLVABLE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2024-02-22 US disclosed
US-20240060014-A1 LOW-WATER COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2024-02-22 US disclosed
EP-2756067-A1 MICROCAPSULE COMPOSITIONS COMPRISING PH TUNEABLE DI-AMIDO GELLANTS The Procter & Gamble Company (US) 2014-07-23 EP disclosed
US-20130303427-A1 MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS THE PROCTER & GAMBLE COMPANY 2013-11-14 US disclosed
WO-2013039963-A1 MICROCAPSULE COMPOSITIONS COMPRISING PH TUNEABLE DI-AMIDO GELLANTS THE PROCTER & GAMBLE COMPANY (US) 2013-03-21 WO disclosed
WO-2013039964-A1 STABLE WATER-SOLUBLE UNIT DOSE ARTICLES THE PROCTER & GAMBLE COMPANY (US) 2013-03-21 WO disclosed
WO-2013040115-A1 FLUID FABRIC ENHANCER COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2013-03-21 WO disclosed
EP-2570474-A1 Stable water-soluble unit dose articles The Procter and Gamble Company (US) 2013-03-20 EP disclosed
US-20130065813-A1 FLUID FABRIC ENHANCER COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2013-03-14 US disclosed
US-20130065811-A1 STABLE WATER-SOLUBLE UNIT DOSE ARTICLE THE PROCTER & GAMBLE COMPANY 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065811-A1 STABLE WATER-SOLUBLE UNIT DOSE ARTICLE IDUA, AQP1, DLST HSD17B10 4431/4885LMNA 2053/4885NPC1 1968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.