Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743272 | 1.00 | CYP2C19 (0.41) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL6471494 | 0.86 | KMT2A (0.38) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL8463296 | 0.83 | CYP2C19 (0.41) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| Butadiene SCHEMBL8463476 | 0.83 | CYP2C19 (0.41) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL8463320 | 0.82 | CYP2C19 (0.39) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL8465641 | 0.80 | HPGD (0.40) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL6465538 | 0.77 | ALDH1A1 (0.41) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL8011170 | 0.75 | P2RX7 (0.43) | P2RX7HPGDKMT2ANPSR1 | |
| SCHEMBL7636583 | 0.74 | CYP2C19 (0.45) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 | |
| Hydrochloric Acid SCHEMBL7630764 | 0.72 | CYP2C19 (0.40) | CYP2C19P2RX7SMN1; SMN2HPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971962-A1 | CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS | THE DOW CHEMICAL COMPANY (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045337-A1 | CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS | THE DOW CHEMICAL COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |